Why is Lex Luthor Superman’s Antithesis?

While discussing the "Wonder Woman" movie this weekend (it's awesome, go see it if you haven't already!), I started thinking about how DC organizes its heroes and villains into duos of opposites.

So Batman, the champion of justice, is opposed by The Joker, the champion of random meaninglessness. There can be no justice in a world where fate is usurped by chaos.

Wonder Woman, the champion of peace and all that is noble in humanity, is opposed by Ares, the god of war who believes all humans are evil and worthless.

Which brings me to Superman, and for the life of me I can't quite put my finger on why Lex Luthor is his opposite.

So I'm asking you -- what's your best explanation for why Lex is Superman's antithesis?