On the 8th Day of Anime Japan Gave to me:
Touma Confronts Misaka
From A Certain Scientific Railgun comes this clip which honestly spans a bit more then a single scene but though cheating a bit here you're sure to understand once you see it how powerful it is as a whole. Here we have Touma confronting Misake over her decision to sacrifice herself for the highly uncertain chance that it will save the lives of her clones. It is just a highly emotionally charged encounter from one of my favorite anime so I needed to share it with you all !